Ultra-high risk for psychosis

Ultra-high risk for psychosis


Ultra-high Risk for Psychosis Research focuses on young people who may be at increased risk of going on to develop schizophrenia and other psychotic disorders.

Why is this research area important?

Ultra-high risk research has the potential to clarify risk and protective factors for psychotic disorders in young people and to identify the most effective interventions for delaying or preventing the onset of psychotic disorders in high risk young people.

Key questions

- What factors best identify young people who are at highest risk of going on to develop schizophrenia and other psychotic disorders?
- What are the psychosocial and neurobiological mechanisms of the onset of psychotic disorders?
- What are the most effective ways to improve the best results for young people, including treating existing symptoms, reducing the onset of psychotic and non-psychotic disorders, and improving functional outcomes?


University of Manchester, University of Birmingham, Brain & Mind Research Institute, Psychiatric Universities Clinic, Switzerland, Integrated Psychiatry Winterthur, Switzerland, University Hospital Jena, Germany, University of Copenhagen, University of Hong Kong, Medical University of Vienna, Buongkok Green Medical Park, Singapore, Academic Medical Centre, The Netherlands.

Research Leader

Professor Barnaby Nelson
Head, Ultra-high Risk for Psychosis Research
Research Interests:
Ultra-high risk for psychosis, prediction research, psychopathology and phenomenology, psychotherapy for psychosis


  • Connie Markulev
  • Dr Suzie Lavoie
  • Jessica Hartmann
  • Meredith McHugh
  • Marija Strmota
  • Emily Li
  • Anneliese Spiteri-Staines
  • Nuwan Leitan